Induction of Apoptosis in Human Breast Adenocarcinoma Cells MCF-7 by Monapurpyridine A, a New Azaphilone Derivative from Monascus purpureus NTU 568
A new azaphilonidal derivative, monapurpyridine A (MPA), has recently ucsb gaucho blue been isolated from the fermented products of Monascus purpureus NTU 568.The structure of MPA was elucidated by nuclear magnetic resonance (1H-NMR, 13C-NMR, COSY, HMQC, and HMBC) and other spectroscopic analyses.Biological evaluation revealed that MPA could induce